Highly Efficient Allylation of Aldehydes Promoted by Maleic Acid in Aqueous Media

Gui-long Li; Gang Zhao

doi:10.1055/s-2005-917088

LETTER

Highly Efficient Allylation of Aldehydes Promoted by Maleic Acid in Aqueous Media

Gui-long Li, Gang Zhao*
Laboratory of Modern Synthetic Organic Chemistry, Key Laboratory of Organofluorine Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, 354 FengLin Lu, Shanghai 200032, P. R. of China
Fax: +86(21)64166128; e-Mail: zhaog@mail.sioc.ac.cn;

Abstract

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Abstract

A highly efficient promoter for allylation of aldehydes in aqueous media was developed. Under the promotion of maleic acid, the allylation of various aldehydes can be finished in a short period of reaction time to afford the corresponding homoallylic alcohols in high to quantitative yields.

Key words

aldehydes - allylation - aqueous media - allyltributyltin - maleic acid

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References

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